For years, goldenseal root (Hydrastis canadensis) has been a cornerstone in herbal medicine, valued for its high berberine content and immune-supporting properties. But today, goldenseal faces a serious challenge: overharvesting. As demand outpaces supply, wild goldenseal populations in North America are rapidly declining, placing this plant at risk.
At Animal Essentials, our mission has always been to care for pets and the planet. That’s why we made the decision to replace goldenseal with Oregon grape root (Mahonia aquifolium) in our updated immune-support formula: Resist & Renew.
Why the Switch from Goldenseal to Oregon Grape?
1. Goldenseal is threatened by overharvesting.
Goldenseal has become one of the most at-risk herbs in North America, with wild populations shrinking due to high demand in the herbal marketplace. Responsible herbalists now recognize the urgent need to find alternatives that protect this plant for future generations.
2. Oregon grape is rich in the same active compound.
Both goldenseal and Oregon grape contain berberine, an alkaloid that has been widely studied for its antimicrobial and immune-supporting properties. This means Oregon grape provides many of the same benefits as goldenseal, but without contributing to the decline of a vulnerable species.
3. Oregon grape is more sustainable to harvest.
Oregon grape grows abundantly in the western United States and Canada, making it a renewable and eco-friendly alternative. Unlike goldenseal, its populations are stable, and it can be harvested in a way that supports long-term ecological health.
The Power of Berberine
Berberine is what gives both goldenseal and Oregon grape their characteristic yellow color — and much of their herbal strength. This compound has been traditionally valued for:
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Supporting the body’s natural defenses.
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Helping maintain microbial balance.
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Promoting overall resilience and wellness.
By choosing Oregon grape, Resist & Renew maintains these berberine-driven benefits while aligning with a stronger ethic of sustainability.
Why Animal Essentials’ Resist & Renew?
With Resist & Renew, pets still receive the immune-supporting synergy of echinacea and berberine-rich herbs. But now, the formula is even more in tune with our values: caring for the Earth as much as we care for our animals.
Crafted in our cGMP-certified U.S. facility with human-grade herbs and no unnecessary fillers, Resist & Renew represents a step forward — not just for immune health, but for the sustainability of herbal medicine itself.
Support Immune Health, Sustainably
By choosing Resist & Renew, you’re not only supporting your pet’s immune system — you’re also helping reduce pressure on endangered goldenseal populations. It’s one small but meaningful way pet parents can make a difference, ensuring that nature’s gifts remain available for generations to come.